{"id":"E05","lang":"en","question":"What upfront payment did AstraZeneca pay insitro?","answer":[{"text":"The disclosed upfront commitment is US$40 million: insitro’s October 15, 2026 announcement says it will receive that amount under its AstraZeneca collaboration.","fact_ids":["f1"]},{"text":"The announcement also lists up to approximately US$1.46 billion in potential discovery, development and commercial milestones, plus single-digit royalties.","fact_ids":["f2","f3"]}],"facts":[{"id":"f1","claim":"Upfront commitment","value":"USD 40,000,000","as_of":"2026-10-15","source":"https://www.insitro.com/news/insitro-announces-a-strategic-collaboration-with-astrazeneca-for-ai-enabled-discovery-of-novel-therapeutics-for-mash-and-cardiomyopathies/","quote":"$40 million upfront"},{"id":"f2","claim":"Potential milestone ceiling","value":"Approximately USD 1,460,000,000","as_of":"2026-10-15","source":"https://www.insitro.com/news/insitro-announces-a-strategic-collaboration-with-astrazeneca-for-ai-enabled-discovery-of-novel-therapeutics-for-mash-and-cardiomyopathies/","quote":"$1.46 billion"},{"id":"f3","claim":"Royalties","value":"Single-digit royalties on potential global commercial sales","as_of":"2026-10-15","source":"https://www.insitro.com/news/insitro-announces-a-strategic-collaboration-with-astrazeneca-for-ai-enabled-discovery-of-novel-therapeutics-for-mash-and-cardiomyopathies/","quote":"single-digit royalties"}],"undisclosed":{"text":"The checked public announcement does not establish that the upfront payment has already been received or disclose exact royalty tiers.","source":"https://www.insitro.com/news/insitro-announces-a-strategic-collaboration-with-astrazeneca-for-ai-enabled-discovery-of-novel-therapeutics-for-mash-and-cardiomyopathies/","as_of":"2026-10-22","quote":"will receive","scope":"Only the specific primary documents cited in this card were checked; absence is not a claim about all public disclosures."},"verified_at":"2026-10-22","coverage":"partial","limitations":["Disclosed contractual amount; cash receipt is not verified."]}