What upfront payment did AstraZeneca pay insitro?
The disclosed upfront commitment is US$40 million: insitro’s October 15, 2026 announcement says it will receive that amount under its AstraZeneca collaboration. [1]
The announcement also lists up to approximately US$1.46 billion in potential discovery, development and commercial milestones, plus single-digit royalties. [1]
Dated evidence
| Claim | Value | As of | Source and original quotation |
|---|---|---|---|
| Upfront commitment | USD 40,000,000 | 2026-10-15 | Primary source$40 million upfront |
| Potential milestone ceiling | Approximately USD 1,460,000,000 | 2026-10-15 | Primary source$1.46 billion |
| Royalties | Single-digit royalties on potential global commercial sales | 2026-10-15 | Primary sourcesingle-digit royalties |
Not disclosed in the public documents
The checked public announcement does not establish that the upfront payment has already been received or disclose exact royalty tiers. Document reviewed 2026-10-22
will receive